09.02.2009

Results from NCI Five-Dose Study of PharmaGap Cancer Drug Expected Late September

Ottawa, Ontario/September 2, 2009 – PharmaGap Inc. (TSX-V: GAP; OTC.BB: PHRGF) (“PharmaGap” or “the Company”) today announced that results are expected in late September from the United States National Cancer Institute (NCI) follow-up study of the company’s lead drug GAP-107B8. 

Results from the initial NCI single dose study released on August 24 showed greater than 50% effect of GAP-107B8 in reduction of cancer cell growth in 26 of the 57 human cancer cell lines tested. Compelling results were found in all 9 cancer types tested, with very positive results in melanoma, breast, central nervous system, and prostate cancers.

The initial test used a single low dose (10μM) to evaluate the effect of GAP-107B8 against the 57 cancer cell lines in the test. In specific melanoma, breast, central nervous system, and prostate cancer cell lines, growth inhibition of 100% was observed (announcement of results can be found on the Company’s website www.pharmagap.com).

Following these compelling results in the initial one-dose testing protocol, GAP-107B8 was selected for testing by the NCI in the same NCI-60 tumour cell panel using five dose concentrations. This range of doses is intended to further examine the drug’s effectiveness in human cancer tumour cells, to allow further characterization of the drug’s activity against various cancer types, and to provide insight into its method of action.

The NCI-60 protocol tests a wide variety of cancers, including breast, colorectal, lung, ovarian, kidney, prostate, leukemia and various central nervous system cancers and melanomas.

About The National Cancer Institute
The National Cancer Institute (NCI), located in Bethesda, MD is an institute of the National Institutes of Health, the primary U.S. Federal Agency for conducting and supporting medical research. The NCI has a mandate to select and screen novel drug compounds that could potentially make a material difference in the “war against cancer”.  Selection to the NCI screening program is through a competitive application process. Details on the NCI’s compound screening program can be found at http://dtp.nci.nih.gov/.  More general information on the NCI is found at www.cancer.gov.

About PharmaGap Inc.
PharmaGap Inc. (TSX-V: GAP), based in Ottawa, ON, is a biotechnology company with a core focus on developing novel therapeutic compounds for the treatment of cancer. PharmaGap's research platform targets cellular signalling pathways controlled by Protein Kinase C (PKC) isoforms. PharmaGap's lead drug compound, PhG-alpha-1, is in preclinical development and targets PKC alpha. The Company's strategy is to out-license drug compounds to larger life sciences companies at the preclinical stage. For more information on PharmaGap please visit the Company's website at www.pharmagap.com.

For information relating to this Release, please contact:
Robert McInnis, President & CEO
(613) 990-9551 bmcinnis@pharmagap.com

Note: The TSX-Venture Exchange does not accept responsibility for the adequacy or accuracy of this release. No Securities Commission or other regulatory authority having jurisdiction over PharmaGap has approved or disapproved of the information contained herein. This release contains forward looking statements that may not occur or may change materially.